Pharmacogenomics is revolutionizing personalized medicine for children by optimizing drug dosing based on an individual's genetic characteristics. This approach ensures safer and more effective treatments. Numerous studies and research projects have explored the clinical implementation and research directions of pharmacogenomics in pediatric patients. Pharmacogenomics has been shown to have a significant impact on drug metabolism and response, particularly in medications such as mercaptopurine and thiopurine, where genetic variations in the thiopurine S-methyltransferase gene have been linked to adverse drug reactions. The field of pharmacogenomics for drug dosing in children is rapidly advancing, with ongoing research focusing on the impact of genetic variations on drug metabolism and response in pediatric populations.
Key Takeaways:
Pharmacogenomics optimizes drug dosing based on genetic characteristics in children.
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