Cytochrome P450 Genotyping in Drug Metabolism: Practical Applications in Pharmacotherapy

Have you ever wondered why a medication that works perfectly for one person may not have the same effect on another? The answer lies in our genes. Our genetic makeup can significantly influence how our bodies metabolize and respond to drugs, and this is where cytochrome P450 genotyping comes into play.
Cytochrome P450 (CYP450) enzymes are a group of enzymes responsible for the metabolism of around 90 percent of drugs in the body. Genetic variability in these enzymes can lead to variations in drug response and metabolism among individuals, making personalized medicine a crucial aspect of pharmacotherapy.

Key Takeaways in Cytochrome P450 Genotyping:

Cytochrome P450 (CYP450) enzymes play a vital role in drug metabolism.
Genetic variations in CYP450 enzymes can result in variations in drug response and metabolism among individuals.
Cytochrome P450 genotyping enables personalized drug therapy and optimization of treatment outcomes.
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